Can verses become "too familiar"?

I've been thinking lately about some of the most well known verses in the Bible, and wondering whether or not some of them become too familiar to us and therefore lose significance. Many verses could be mentioned, but the one that comes to mind is Proverbs 3:5-6. In case you don't have it memorized (shame on you! Just kidding), it says, "Trust in the Lord with all your heart and lean not on your own understanding; in all your ways acknowledge him and he will make straight your paths." This is one of the verses we will be using tomorrow night for youth group, particularly trying to answer the question "how do I know when I'm actually spending time with God?" My thesis if you will is that simply activities such as reading the Bible, going to church, going to youth group, and other activities do not guarantee that you are spending time with God. Basically, the simple formula "reading the Bible = spending time with God" is not always true.

For me, Proverbs 3:5-6 is helpful in answering the question about spending time with God. I believe it sheds some light on the issue, namely that if reading the Bible doesn't always equate to time spent with God, trusting in God with all my heart and acknowledging him in all of my life does indicate I'm spending time with him. And if that is the case, then it can often be that the "less spiritual" things like going to school, doing homework, going to work, eating a meal, exercising, and so on can indeed be times spent with the Lord. It seems to me that Christians do a great disservice when we believe (or teach!) that the spiritual things are prayer, solitude, studying the Bible, and church attendance and other things mentioned above are not-so-spiritual. In the end, God is with us at all times by the Holy Spirit living in us, and therefore we are always spending time with God; or, at the very least every activity can be spending time with God if we are trusting in him and acknowledging him in our lives.

What other verses are "all too common" verses for us today? How can another look at them help us grow in our walk with Christ?